Oxalate CoA-transferase
| Oxalate CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.3.2 | ||||||||
| CAS no. | 9026-17-9 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Oxalate CoA-transferase (EC 2.8.3.2) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme characterised from Pseudomonas oxalaticus are oxalic acid and succinyl-CoA. Its products are succinic acid and oxalyl-CoA.[1] The enzyme is similar to one found in Oxalobacter formigenes, a bacterium present in human gut.[2][3]
This enzyme is a transferase, specifically a CoA-transferase. The systematic name of this enzyme class is succinyl-CoA:oxalate CoA-transferase. Other names in common use include succinyl-beta-ketoacyl-CoA transferase, and oxalate coenzyme A-transferase.[4]
References
- ↑ Quayle JR, Keech DB, Taylor GA (1961). "Carbon assimilation by Pseudomonas oxalaticus (OXI). 4. Metabolism of oxalate in cell-free extracts of the organism grown on oxalate". Biochem. J. 78 (2): 225–36. doi:10.1042/bj0780225. PMC 1205258. PMID 16748872.
- ↑ Heider, Johann (2001). "A new family of CoA-transferases". FEBS Letters. 509 (3): 345–349. doi:10.1016/S0014-5793(01)03178-7. PMID 11749953.
- ↑ Stewart, Colin S.; Duncan, Sylvia H.; Cave, David R. (2004). "Oxalobacter formigenes and its role in oxalate metabolism in the human gut". FEMS Microbiology Letters. 230 (1): 1–7. doi:10.1016/S0378-1097(03)00864-4. PMID 14734158.
- ↑ Enzyme 2.8.3.2 at KEGG Pathway Database.