Cinnamoyl-CoA:phenyllactate CoA-transferase
| cinnamoyl-CoA:phenyllactate CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.3.17 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Cinnamoyl-CoA:phenyllactate CoA-transferase (EC 2.8.3.17) is an enzyme that catalyzes the chemical reaction
-cinnamoyl-CoA.svg.png)
-3-phenyllactic_acid.svg.png)
-3-phenyllactyl-CoA.svg.png)
The two substrates of this enzyme characterised from Clostridium sporogenes are cinnamoyl-CoA and (R)-3-phenyllactic acid. Its products are cinnamic acid and (R)-3-phenyllactyl-CoA.[1][2][3]
This enzyme belongs to the CoA-transferase family. The systematic name of this enzyme class is (E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase. This enzyme is also called FldA.[4]
References
- ↑ Dickert S, Pierik AJ, Linder D, Buckel W (2000). "The involvement of coenzyme A esters in the dehydration of (R)-phenyllactate to (E)-cinnamate by Clostridium sporogenes". Eur. J. Biochem. 267 (12): 3874–84. doi:10.1046/j.1432-1327.2000.01427.x. PMID 10849007.
- ↑ Buckel, W. (2001). "Unusual enzymes involved in five pathways of glutamate fermentation". Applied Microbiology and Biotechnology. 57 (3): 263–273. doi:10.1007/s002530100773. PMID 11759672.
- ↑ Dodd, Dylan; Spitzer, Matthew H.; Van Treuren, William; et al. (2017). "A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites". Nature. 551 (7682): 648–652. doi:10.1038/nature24661. PMC 5850949. PMID 29168502.
- ↑ Enzyme 2.8.3.17 at KEGG Pathway Database.
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