Flavonol 3-sulfotransferase

Flavonol 3-sulfotransferase
Identifiers
EC no.2.8.2.25
CAS no.121855-10-5
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

A flavonol 3-sulfotransferase (EC 2.8.2.25) is an enzyme that catalyzes the general chemical reaction

 
 
 
 
Rightward reaction arrow
 
 
 
flavanonol 3-O-sulfate +
 

It uses the cofactor 3'-phosphoadenosine-5'-phosphosulfate (PAPS) and gives adenosine 3',5'-bisphosphate as a byproduct. For example, the enzyme characterised from Flaveria chlorifolia converts quercetin to quercetin 3-O-sulfate :[1]

+ PAPS
 
 
 
 
Rightward reaction arrow
 
 
 
+ adenosine 3',5'-
bisphosphate
 

This enzyme is a transferase of sulfotransferase type, which transfer sulfate groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase.[2]

References

  1. ↑ Varin L, Ibrahim RK (July 1989). "Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from Flaveria chlorifolia". Plant Physiology. 90 (3): 977–81. doi:10.1104/pp.90.3.977. PMC 1061831. PMID 16666908.
  2. ↑ Enzyme 2.8.2.25 at KEGG Pathway Database.