Lachnospiraceae
| Lachnospiraceae | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Kingdom: | Bacillati |
| Phylum: | Bacillota |
| Class: | Clostridia |
| Order: | Eubacteriales |
| Family: | Lachnospiraceae Rainey 2010[1] |
| Type genus | |
| Lachnospira Bryant and Small 1956 (Approved Lists 1980) | |
| Genera | |
|
See text | |
| Synonyms | |
| |
Lachnospiraceae is a family of predominantly obligately anaerobic bacteria in the order Eubacteriales. Members of the family are common in the digestive tracts of mammals, including the rumen and the human gut microbiota. Many members ferment carbohydrates and produce short-chain fatty acids, including acetate and butyrate.[2]
Lachnospiraceae constituted the largest family represented in the Hungate1000 collection of cultured rumen microorganisms. Genomic analysis of the collection identified members with genes involved in the degradation of cellulose, hemicellulose, pectin, and other polysaccharides.[3]
Changes in the abundance and composition of Lachnospiraceae have been reported in studies of human disease, including colorectal cancer.[4] Colonization by a particular Lachnospiraceae strain also promoted diabetes in genetically obese germ-free mice, although such findings do not necessarily apply uniformly across this taxonomically diverse family.[5]
Taxonomy
The type genus is Lachnospira.[1] LPSN places Lachnospiraceae in the order Eubacteriales, whereas the Genome Taxonomy Database places it in the order Lachnospirales.[6]
Genera
As of July 2026, LPSN recognized 103 genera with validly published and correct names in Lachnospiraceae:[1]
- Acetatifactor
- Acetitomaculum
- Agathobacter
- Alitiscatomonas
- Allocoprococcus
- Anaerobium
- Anaerobutyricum
- Anaerocolumna
- Anaerolentibacter
- Anaeromicropila
- Anaeropeptidivorans
- Anaerosacchariphilus
- Anaerostipes
- Anaerotaenia
- Anaerotignum
- Anthropogastromicrobium
- Bilifractor
- Blautia
- Bovifimicola
- Brotaphodocola
- Brotonthovivens
- Butyribacter
- Butyrivibrio
- Catenibacillus
- Catonella
- Cellulosilyticum
- Chakrabartyella
- Chordicoccus
- Claveliimonas
- Coprococcus
- Cuneatibacter
- Diplocloster
- Dorea
- Eisenbergiella
- Enterocloster
- Eshraghiella
- Extibacter
- Faecalicatena
- Faecalimonas
- Falcatimonas
- Frisingicoccus
- Fusibacillus
- Fusicatenibacter
- Gallintestinimicrobium
- Herbinix
- Hespellia
- Holtiella
- Hominifimenecus
- Hominisplanchenecus
- Hoministercoradaptatus
- Hominiventricola
- Howardella
- Johnsonella
- Jutongia
- Kineothrix
- Konateibacter
- Lachnoanaerobaculum
- Lachnobacterium
- Lachnospira
- Lachnotalea
- Lacrimispora
- Laedolimicola
- Lientehia
- Marvinbryantia
- Mediterraneibacter
- Merdimonas
- Mobilisporobacter
- Mobilitalea
- Moryella
- Muricomes
- Muricoprocola
- Murimonas
- Naizhengia
- Natranaerovirga
- Novisyntrophococcus
- Oliverpabstia
- Oribacterium
- Otoolea
- Pararoseburia
- Parasporobacterium
- Petralouisia
- Porcibacter
- Porcincola
- Pseudobutyrivibrio
- Pseudocoprococcus
- Robinsoniella
- Roseburia
- Sanxizhangella
- Schaedlerella
- Sellimonas
- Shuttleworthella
- Sporobacterium
- Sporofaciens
- Stomatobaculum
- Suilimivivens
- Suipraeoptans
- Syntrophococcus
- Variimorphobacter
- Velocimicrobium
- Ventrimonas
- Waltera
- Yonghella
- Zhenhengia
Phylogeny
The following reduced phylogeny is based on GTDB release R11-RS232. [6][7]
| 120 marker proteins based GTDB R11-RS232 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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References
- 1 2 3 "Family: Lachnospiraceae". List of Prokaryotic names with Standing in Nomenclature. Leibniz Institute DSMZ. Retrieved 26 July 2026.
- ↑ Meehan, Conor J.; Beiko, Robert G. (2014). "A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria". Genome Biology and Evolution. 6 (3): 703–713. doi:10.1093/gbe/evu050. PMC 3971600. PMID 24625961.
- ↑ Seshadri, Rekha; Leahy, Sinead C.; Attwood, Graeme T.; et al. (2018). "Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection". Nature Biotechnology. 36 (4): 359–367. doi:10.1038/nbt.4110. PMC 6118326. PMID 29553575.
- ↑ Xia, Li C.; Liu, Gang; Gao, Yingxin; Li, Xiaoxin; Pan, Hongfei; Ai, Dongmei (2019). "Identifying gut microbiota associated with colorectal cancer using a zero-inflated lognormal model". Frontiers in Microbiology. 10 826. doi:10.3389/fmicb.2019.00826. PMC 6491826. PMID 31068913.
- ↑ Kameyama, Keishi; Itoh, Kikuji (2014). "Intestinal colonization by a Lachnospiraceae bacterium contributes to the development of diabetes in obese mice". Microbes and Environments. 29 (4): 427–430. doi:10.1264/jsme2.ME14054. PMC 4262368. PMID 25283478.
- 1 2 "GTDB release R11-RS232". Genome Taxonomy Database. Retrieved 26 July 2026.
- ↑ "bac120_r232.sp_labels.tree" (Newick). Genome Taxonomy Database. Retrieved 26 July 2026.
