Trihydroxypterocarpan dimethylallyltransferase
| Trihydroxypterocarpan dimethylallyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.36 | ||||||||
| CAS no. | 70851-94-4 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Trihydroxypterocarpan dimethylallyltransferase (EC 2.5.1.36, dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan dimethylallyltransferase, dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl transferase, dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethyltransferase) is an enzyme with systematic name dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase.[1] It catalyses two related chemical reactions in which an prenyl unit is added to a phenyl ring. The enzyme uses dimethylallyl pyrophosphate to provide the five-carbon fragment, with pyrophosphate (PPi) as a byproduct:[2]
The enzyme can also catalyse the addition of the prenyl group at the alternative position next to the oxygen of the dihydropyran ring, giving 4-dimethylallylglycinol.
These compounds are intermediates in glyceollin biosynthesis in soybean.[3] The final step is catalysed by the enzyme glyceollin synthase.[4]
References
- ↑ Leube J, Grisebach H (1983). "Further studies on induction of enzymes of phytoalexin synthesis in soybean and cultured soybean cells". Z. Naturforsch. C: Biosci. 38 (9–10): 730–735. doi:10.1515/znc-1983-9-1011.
- ↑ Enzyme 2.5.1.36 at KEGG Pathway Database.
- ↑ Zähringer U, Schaller E, Grisebach H (1981). "Induction of phytoalexin synthesis in soybean. Structure and reactions of naturally occurring and enzymatically prepared prenylated pterocarpans from elicitor-treated cotyledons and cell cultures of soybean". Z. Naturforsch. C. 36 (3–4): 234–241. doi:10.1515/znc-1981-3-409.
- ↑ Welle R, Grisebach H (1988). "Induction of phytoalexin synthesis in soybean: enzymatic cyclization of prenylated pterocarpans to glyceollin isomers". Arch. Biochem. Biophys. 263 (1): 191–8. doi:10.1016/0003-9861(88)90627-3. PMID 3369863.
External links
- Trihydroxypterocarpan+dimethylallyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)