Pinosylvin synthase

Pinosylvin synthase
Identifiers
EC no.2.3.1.146
CAS no.72994-49-1
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

Pinosylvin synthase (EC 2.3.1.146) is an enzyme that catalyzes the chemical reaction

+ 3
 
 
 
4 CO2
Rightward reaction arrow with minor product(s) to top right
 
 
 
 

The enzyme combines one unit of cinnamoyl-CoA with three of malonyl-CoA to form the stilbene, pinosylvin, with coenzyme A and carbon dioxide as byproducts. The product is produced in response to fungal attack on the pine tree Pinus sylvestris.[1][2]

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing). Other names in common use include stilbene synthase, and pine stilbene synthase.[3]

References

  1. ↑ Gehlert R (1990). "Stilbene Synthase from Seedlings of Pinus sylvestris : Purification and Induction in Response to Fungal Infection". Molecular Plant-Microbe Interactions. 3 (6): 444. Bibcode:1990MPMI....3..444G. doi:10.1094/MPMI-3-444.
  2. ↑ Valletta A, Iozia LM, Leonelli F (January 2021). "Impact of Environmental Factors on Stilbene Biosynthesis". Plants. 10 (1): 90. Bibcode:2021Plnts..10...90V. doi:10.3390/plants10010090. PMC 7823792. PMID 33406721.
  3. ↑ Enzyme 2.3.1.146 at KEGG Pathway Database.