Pantetheine kinase
| Pantetheine kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.1.34 | ||||||||
| CAS no. | 9026-49-7 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Pantetheine kinase (EC 2.7.1.34) is an enzyme that catalyzes the chemical reaction
The enzyme converts pantetheine to phosphopantetheine by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP). This is part of the biosynthetic pathway to coenzyme A.[1][2]
This enzyme is a transferases, specifically one transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:pantetheine 4'-phosphotransferase. It is also called pantetheine kinase (phosphorylating).[3]
References
- ↑ Novelli GD (September 1953). "Enzymatic synthesis and structure of CoA". Federation Proceedings. 12 (3): 675–81. PMID 13107738.
- ↑ Schomburg, Dietmar; Stephan, Dörte (1997). "Pantetheine kinase". Enzyme Handbook 13. pp. 747–749. doi:10.1007/978-3-642-59176-1_145. ISBN 978-3-540-62608-4.
- ↑ Enzyme 2.7.1.34 at KEGG Pathway Database.
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