N6-hydroxylysine O-acetyltransferase
| N6-hydroxylysine O-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.102 | ||||||||
| CAS no. | 101077-53-6 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
N6-hydroxylysine O-acetyltransferase (EC 2.3.1.102) is an enzyme that catalyzes the chemical reaction
-hydroxy-L-lysine.svg.png)
-acetyl-N(6)-hydroxy-L-lysine.svg.png)
The two substrates of this enzyme characterised from Escherichia coli are N(6)-hydroxy-L-lysine and acetyl-CoA. Its products are N(6)-acetyl-N(6)-hydroxy-L-lysine and coenzyme A.[1][2]
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase. Other names in common use include N6-hydroxylysine:acetyl CoA N6-transacetylase, N6-hydroxylysine acetylase, and acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase. It participates in lysine degradation and the biosynthesis of the siderophore, aerobactin.[2][3]
References
- ↑ Coy M, Paw BH, Bindereif A, Neilands JB (1986). "Isolation and properties of N epsilon-hydroxylysine:acetyl coenzyme A N epsilon-transacetylase from Escherichia coli pABN11". Biochemistry. 25 (9): 2485–9. doi:10.1021/bi00357a030. PMID 3521734.
- 1 2 de Lorenzo V, Bindereif A, Paw BH, Neilands JB (1986). "Aerobactin biosynthesis and transport genes of plasmid ColV-K30 in Escherichia coli K-12". J. Bacteriol. 165 (2): 570–8. doi:10.1128/jb.165.2.570-578.1986. PMC 214457. PMID 2935523.
- ↑ Enzyme 2.3.1.102 at KEGG Pathway Database.