Mannosylfructose-phosphate phosphatase
| Mannosylfructose-phosphate phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.3.79 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Mannosylfructose-phosphate phosphatase (EC 3.1.3.79, mannosylfructose-6-phosphate phosphatase, MFPP) is an enzyme with systematic name β-D-ructofuranosyl-α-D-mannopyranoside-6F-phosphate phosphohydrolase.[1] It catalyses the following chemical reaction which removes a phosphate group (Pi) by hydrolysis:
This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires magnesium, Mg2+, for activity. The starting material is produced from GDP-mannose and fructose 6-phosphate by the enzyme mannosylfructose-phosphate synthase and the product is an osmolyte which protexts the organism from osmotic shock.[2]
References
- ↑ Enzyme 3.1.3.79 at KEGG Pathway Database.
- ↑ Torres LL, Salerno GL (September 2007). "A metabolic pathway leading to mannosylfructose biosynthesis in Agrobacterium tumefaciens uncovers a family of mannosyltransferases". Proceedings of the National Academy of Sciences of the United States of America. 104 (36): 14318–23. Bibcode:2007PNAS..10414318T. doi:10.1073/pnas.0706709104. PMC 1964871. PMID 17728402.
External links
- Mannosylfructose-phosphate+phosphatase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Category:
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