Mannokinase
| Mannokinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.1.7 | ||||||||
| CAS no. | 9030-54-0 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Mannokinase (EC 2.7.1.7) is an enzyme that catalyzes the chemical reaction
The enzyme characterised from Schistosoma mansoni converts the hexose sugar, L-mannose (shown in its cyclic form) to L-mannose 6-phosphate by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP).[1]
This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-mannose 6-phosphotransferase. Other names in common use include mannokinase (phosphorylating), and D-fructose (D-mannose) kinase.[2]
References
- ↑ Bueding, Ernest; MacKinnon, Joan A. (1955). "Hexokinases of Schistosoma mansoni". Journal of Biological Chemistry. 215 (2): 495–506. doi:10.1016/S0021-9258(18)65971-X. PMID 13242546.
- ↑ Enzyme 2.7.1.7 at KEGG Pathway Database.
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