Lysine N-acetyltransferase

Lysine N-acetyltransferase
Lysine N-acetyltransferase (EIS) hexamer, Mycobacterium tuberculosis
Identifiers
EC no.2.3.1.32
CAS no.37257-12-8
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Lysine N-acetyltransferase (EC 2.3.1.32) is an enzyme characterised from beef liver that catalyzes the chemical reaction

2D representation of the chemical structure of Q20816880.
lysine
+
 
2D representation of the chemical structure of acetyl phosphate.
acetyl phosphate
 
 
H3PO4
Reversible left-right reaction arrow with minor forward product(s) to top right and minor reverse substrate(s) from bottom right
 
H3PO4
 
2D representation of the chemical structure of acetyllysine .
acetyllysine

The two substrates of this enzyme are L-lysine and acetyl phosphate. Its products are acetyllysine and phosphoric acid.[1]

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-phosphate:L-lysine N6-acetyltransferase. Other names in common use include lysine acetyltransferase, and acetyl-phosphate:L-lysine 6-N-acetyltransferase. This enzyme participates in lysine degradation.[2]

References

  1. ↑ PAIK WK, KIM S (1964). "Enzymic synthesis of ϵ-N-acetyl-l-lysine". Arch. Biochem. Biophys. 108 (2): 221–9. doi:10.1016/0003-9861(64)90379-0. PMID 14240571.
  2. ↑ Enzyme 2.3.1.32 at KEGG Pathway Database.


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