Luteolin 7-O-glucuronosyltransferase
| Luteolin 7-O-glucuronosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.189 | ||||||||
| CAS no. | 115490-49-8 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Luteolin 7-O-glucuronosyltransferase (EC 2.4.1.189) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme characterised from rye are the flavone, luteolin. and UDP-glucuronate which react to give the glucuronide, luteolin 7-O-glucuronide, by adding a sugar acid at one of the phenolic hydroxy groups, with uridine diphosphate (UDP) as byproduct.[1]
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucuronate:luteolin 7-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase, and LGT.[2]
References
- ↑ Schulz M, Weissenbock G (1988). "3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale". Phytochemistry. 27 (5): 1261–1267. doi:10.1016/0031-9422(88)80175-4.
- ↑ Enzyme 2.4.1.189 at KEGG Pathway Database.
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