Luteolin 7-O-glucuronosyltransferase

Luteolin 7-O-glucuronosyltransferase
Identifiers
EC no.2.4.1.189
CAS no.115490-49-8
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Luteolin 7-O-glucuronosyltransferase (EC 2.4.1.189) is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme characterised from rye are the flavone, luteolin. and UDP-glucuronate which react to give the glucuronide, luteolin 7-O-glucuronide, by adding a sugar acid at one of the phenolic hydroxy groups, with uridine diphosphate (UDP) as byproduct.[1]

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucuronate:luteolin 7-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase, and LGT.[2]

References

  1. ↑ Schulz M, Weissenbock G (1988). "3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale". Phytochemistry. 27 (5): 1261–1267. doi:10.1016/0031-9422(88)80175-4.
  2. ↑ Enzyme 2.4.1.189 at KEGG Pathway Database.