Luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase
| Luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.191 | ||||||||
| CAS no. | 115490-50-1 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase (EC 2.4.1.191) is an enzyme that catalyzes a chemical reaction which converts a luteolin di-glucuronide, luteolin 7-O-(β-D-glucuronosyl-(1→2)-β-D-glucuronide, into a specific triglucuronide with the chemical name luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide. The enzyme characterised from the leaves of Secale cereale transfers the third sugar acid from UDP-glucuronate, giving uridine diphosphate (UDP) as a byproduct.[1]
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This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-diglucuronide, glucuronosyltransferase, UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase, UDPglucuronate:luteolin, 7-O-diglucuronide-4'-O-glucuronosyl-transferase, and LDT.[2]
References
- ↑ Schulz M, Weissenbock G (1988). "3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale". Phytochemistry. 27 (5): 1261–1267. doi:10.1016/0031-9422(88)80175-4.
- ↑ Enzyme 2.4.1.191 at KEGG Pathway Database.
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