| Title | Director | Cast | Genre | Notes |
| 2010 |
| 18 Years Later |
Edoardo Leo | Edoardo Leo, Marco Bonini, Sabrina Impacciatore | Comedy-drama | |
| 20 Cigarettes |
Aureliano Amadei | Vinicio Marchioni, Carolina Crescentini | Drama | |
| Angel of Evil |
Michele Placido | Kim Rossi Stuart, Michele Placido, Filippo Timi, Paz Vega | Crime | |
| Basilicata Coast to Coast |
Rocco Papaleo | Rocco Papaleo, Alessandro Gassman, Giovanna Mezzogiorno | Comedy | |
| Benvenuti al Sud |
Luca Miniero | Claudio Bisio, Alessandro Siani, Angela Finocchiaro, Valentina Lodovini | Comedy | |
|
| Certified Copy |
Abbas Kiarostami | Juliette Binoche, William Shimell | Drama | French-Italian-Belgian co-production |
| Come Undone |
Silvio Soldini | Alba Rohrwacher, Pierfrancesco Favino, | Drama | Berlin Film Festival |
| Dark Love |
Antonio Capuano | Luisa Ranieri, Valeria Golino, Fabrizio Gifuni | Drama | |
| Die |
Dominic James | Elias Koteas, Emily Hampshire, Caterina Murino | Thriller | Canadian-Italian co-production |
| Draquila – L'Italia che trema |
Sabina Guzzanti | Sabina Guzzanti | Documentary | Entered the 2010 Cannes Film Festival |
| The End Is My Beginning |
Jo Baier | Bruno Ganz, Elio Germano | Drama | |
| Exit: una storia personale |
Massimiliano Amato | Luca Guastini | Drama | |
| The Father and the Foreigner |
Ricky Tognazzi | Alessandro Gassman, Amr Waked | Drama | |
| The First Assignment |
Giorgia Cecere | Isabella Ragonese | Drama | |
| The First Beautiful Thing |
Paolo Virzì | Valerio Mastandrea, Micaela Ramazzotti, Stefania Sandrelli, Claudia Pandolfi | Drama | Italian entry for the Best Foreign Language Film at the 83rd Academy Awards |
| From the Waist Up |
Gianfrancesco Lazotti | Cristiana Capotondi, Filippo Nigro, Nicoletta Romanoff | Drama | |
| Gorbaciof |
Stefano Incerti | Toni Servillo, Yang Mi | Drama | |
| Happy Family |
Gabriele Salvatores | Margherita Buy, Diego Abatantuono, Fabrizio Bentivoglio | Comedy | |
| Hayfever |
Laura Luchetti | Andrea Bosca, Diane Fleri, Giulia Michelini | Romance | |
| I Am Love |
Luca Guadagnino | Tilda Swinton, Marisa Berenson | Drama | Music By John Adams |
| Into Paradiso |
Paola Randi | Gianfelice Imparato, Peppe Servillo | Comedy | Entered into the 67th Venice International Film Festival |
| Kiss Me Again |
Gabriele Muccino | Stefano Accorsi, Pierfrancesco Favino | Romance | Sequel of The Last Kiss |
| Loose Cannons |
Ferzan Özpetek | Riccardo Scamarcio, Alessandro Preziosi, Carolina Crescentini, Nicole Grimaudo | Comedy | Entered the 60th Berlin International Film Festival |
| Lost Kisses |
Roberta Torre | Donatella Finocchiaro, Carla Marchese, Piera Degli Esposti | Comedy-drama | Entered into the 68th Venice International Film Festival |
| Love & Slaps |
Sergio Castellitto | Sergio Castellitto, Laura Morante, Enzo Jannacci, Marco Giallini | Comedy | |
| Marriage and Other Disasters |
Nina Di Majo | Margherita Buy, Fabio Volo, Francesca Inaudi | Comedy | |
| Martino's Summer |
Massimo Natale | Treat Williams, Luigi Ciardo | Drama | |
| Men vs. Women |
Fausto Brizzi | Paola Cortellesi, Fabio De Luigi, Sarah Felberbaum, Claudio Bisio | Comedy | |
| Me, Them and Lara |
Carlo Verdone | Carlo Verdone, Laura Chiatti, Anna Bonaiuto, Marco Giallini | Comedy | |
| The Mouth of the Wolf |
Pietro Marcello | Mary Monaco | Documentary | Teddy Award winner |
| News from the Excavations |
Emidio Greco | Giuseppe Battiston, Ambra Angiolini, Iaia Forte | Drama | |
| La nostra vita |
Daniele Luchetti | Elio Germano, Isabella Ragonese, Raoul Bova | Drama | In competition at the 2010 Cannes Film Festival |
| Parents and Children: Shake Well Before Using |
Giovanni Veronesi | Silvio Orlando, Luciana Littizzetto, Michele Placido, Margherita Buy | Comedy | |
| Passione |
John Turturro | John Turturro, Fiorello, Massimo Ranieri, Lina Sastri | Documentary | Entered into the 67th Venice International Film Festival |
| La passione |
Carlo Mazzacurati | Silvio Orlando, Cristiana Capotondi, Stefania Sandrelli, Kasia Smutniak | Comedy-drama | Entered into the 67th Venice International Film Festival |
| La pecora nera |
Ascanio Celestini | Maya Sansa, Giorgio Tirabassi, Ascanio Celestini | Comedy | Entered into the 67th Venice International Film Festival |
| Le Quattro Volte |
Michelangelo Frammartino | Giuseppe Fuda | Drama | |
| A Quiet Life |
Claudio Cupellini | Toni Servillo, Juliane Köhler | Neo-noir | |
| The Santa Claus Gang |
Paolo Genovese | Aldo, Giovanni & Giacomo, Angela Finocchiaro | Comedy | |
| School Is Over |
Valerio Jalongo | Valeria Golino, Vincenzo Amato, Antonella Ponziani | Drama | |
| A Second Childhood |
Pupi Avati | Fabrizio Bentivoglio, Francesca Neri, Lino Capolicchio, Serena Grandi | Drama | |
| The Solitude of Prime Numbers |
Saverio Costanzo | Alba Rohrwacher, Luca Marinelli, Isabella Rossellini | Drama | Entered into the 67th Venice International Film Festival |
| Sorry If I Want to Marry You |
Federico Moccia | Raoul Bova, Michela Quattrociocche, Cecilia Dazzi | Romantic comedy | |
| Sul mare |
Alessandro D'Alatri | Martina Codecasa, Vincenzo Merolla | Romance | |
| Ti presento un amico |
Carlo Vanzina | Raoul Bova, Martina Stella, Barbora Bobuľová | Romantic comedy | |
| The Trick in the Sheet |
Alfonso Arau | Maria Grazia Cucinotta, Geraldine Chaplin, Anne Parillaud | Comedy | |
| Ubaldo Terzani Horror Show |
Gabriele Albanesi | Paolo Sassanelli, Giuseppe Soleri | Horror | |
| Unlikely Revolutionaries |
Lucio Pellegrini | Pierfrancesco Favino, Giuseppe Battiston, Fabio Volo, Claudia Pandolfi | Comedy | |
| The Youngest Son |
Pupi Avati | Christian De Sica, Luca Zingaretti, Laura Morante | Comedy-drama | |
| We Believed |
Mario Martone | Luigi Lo Cascio, Valerio Binasco, Toni Servillo, Luca Zingaretti | Drama | Entered into the 67th Venice International Film Festival |
| The Woman of My Dreams |
Luca Lucini | Alessandro Gassman, Luca Argentero, Valentina Lodovini | Comedy | |
