Leucine N-acetyltransferase
| Leucine N-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.66 | ||||||||
| CAS no. | 75496-56-9 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Leucine N-acetyltransferase (EC 2.3.1.66) is an enzyme characterised from Streptomyces roseus that catalyzes the chemical reaction
The two substrates of this enzyme are L-leucine and acetyl-CoA. Its products are levacetylleucine and coenzyme A. The product is incorporated into the protease inhibitor, leupeptin.[1]
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-leucine N-acetyltransferase. This enzyme is also called leucine acetyltransferase.[2]
References
- ↑ Suzukake S, Hayashi H, Hori M, Umezawa H (1982). "Biosynthesis of leupeptin III. Isolation and properties of an enzyme synthesizing acetyl-L-leucine". J. Antibiot. 33 (8): 857–862. doi:10.7164/antibiotics.33.857. PMID 7429989.
- ↑ Enzyme 2.3.1.66 at KEGG Pathway Database.
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