L-rhamnose isomerase
| L-rhamnose isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.3.1.14 | ||||||||
| CAS no. | 9023-84-1 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a L-rhamnose isomerase (EC 5.3.1.14) is an enzyme that catalyzes the chemical reaction
- L-rhamnose L-rhamnulose
Hence, this enzyme has one substrate, L-rhamnose, and one product, L-rhamnulose.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is L-rhamnose aldose-ketose-isomerase. Other names in common use include rhamnose isomerase, and L-rhamnose ketol-isomerase. This enzyme participates in fructose and mannose metabolism.
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes PDB: 1D8W, PDB: 1DE5, PDB: 1DE6, PDB: 2HCV, PDB: 2I56, and PDB: 2I57.
References
- DOMAGK GF, ZECH R (1963). "On the Decomposition of Desoxy Sugars by Bacterial Enzymes. I. L-Rhamnose Isomerase from Lactobacillus Plantarum". Biochem. Z. 339: 145–53. PMID 14095156.