Hydroxymandelonitrile glucosyltransferase
| Hydroxymandelonitrile glucosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.178 | ||||||||
| CAS no. | 89287-39-8 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hydroxymandelonitrile glucosyltransferase (EC 2.4.1.178) is an enzyme that catalyzes the chemical reaction
-4-hydroxymandelonitrile_%CE%B2-D-glucoside.svg.png)
The two substrates of this enzyme characterised from Triglochin maritima are 4-hydroxymandelonitrile and UDP-glucose. Its products are taxiphillin and uridine diphosphate (UDP).[1] The enzyme is related to (R)-mandelonitrile β-glucosyltransferase (EC 2.4.1.354), which produces prunasin from mandelonitrile. These products are both cyanogenic glucosides.[2]
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:4-hydroxymandelonitrile glucosyltransferase. Other names in common use include cyanohydrin glucosyltransferase, and uridine diphosphoglucose-cyanohydrin glucosyltransferase.[3]
References
- ↑ Hosel W, Schiel O (1984). "Biosynthesis of cyanogenic glucosides: in vitro analysis of the glucosylation step". Arch. Biochem. Biophys. 229 (1): 177–86. doi:10.1016/0003-9861(84)90142-5. PMID 6230992.
- ↑ Poulton JE, Shin SI (1983). "Prunasin biosynthesis by cell-free-extracts from black cherry (Prunus serotina Ehrh) fruits and leaves". Z. Naturforsch. C: Biosci. 38 (5–6): 369–374. doi:10.1515/znc-1983-5-606.
- ↑ Enzyme 2.4.1.178 at KEGG Pathway Database.
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