Homoserine O-acetyltransferase
| Homoserine O-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.31 | ||||||||
| CAS no. | 9030-72-2 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Homoserine O-acetyltransferase (EC 2.3.1.31) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme characterised from Neurospora are homoserine and acetyl-CoA. Its products are O-acetyl-homoserine and coenzyme A.[1]
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-homoserine O-acetyltransferase. Other names in common use include homoserine acetyltransferase, homoserine transacetylase, homoserine-O-transacetylase, and L-homoserine O-acetyltransferase. This enzyme participates in cysteine and methionine metabolism.[2]
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB: 2B61.
References
- ↑ Nagai S, Flavin M (1967). "Acetylhomoserine. An intermediate in the fungal biosynthesis of methionine". J. Biol. Chem. 242 (17): 3884–95. doi:10.1016/S0021-9258(18)95831-X. PMID 6037552.
- ↑ Enzyme 2.3.1.31 at KEGG Pathway Database.