Guanosine phosphorylase
| Guanosine phosphorylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.2.15 | ||||||||
| CAS no. | 9030-28-8 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Guanosine phosphorylase (EC 2.4.2.15) is an enzyme that catalyzes a reversible phosphorolysis reaction
In the forward direction shown, the two substrates of the enzyme characterised from Escherichia coli are guanosine and orthophosphate (Pi). Its products are α-D-ribose 1-phosphate and guanine.[1] It has also been found in rabbit.[2]
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is guanosine:phosphate alpha-D-ribosyltransferase.[3]
References
- ↑ Koszalka, G W; Vanhooke, J; Short, S A; Hall, W W (August 8, 1988). "Purification and properties of inosine-guanosine phosphorylase from Escherichia coli K-12". Journal of Bacteriology. 170 (8): 3493–3498. doi:10.1128/jb.170.8.3493-3498.1988. ISSN 0021-9193. PMC 211319. PMID 3042752.
- ↑ Yamada EW (November 1961). "The phosphorolysis of nucleosides by rabbit bone marrow". The Journal of Biological Chemistry. 236 (11): 3043–6. doi:10.1016/S0021-9258(19)76425-4. PMID 14008731.
- ↑ Enzyme 2.4.2.15 at KEGG Pathway Database.
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