Glucuronokinase

Glucuronokinase
Identifiers
EC no.2.7.1.43
CAS no.9026-62-4
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Glucuronokinase (EC 2.7.1.43) is an enzyme that catalyzes the chemical reaction

ATP +
 
2D representation of the chemical structure of Q78172907.
D-glucuronic acid
 
 
 
Reversible left-right reaction arrow
 
 
 
ADP +
 
2D representation of the chemical structure of Q27102077.
1-phospho-α-D-glucuronic acid

The enzyme characterised from mung bean converts D-glucuronic acid to 1-phospho-α-D-glucuronic acid by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP).[1]

This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-glucuronate 1-phosphotransferase. Other names in common use include glucuronokinase (phosphorylating), and glucurono-glucuronokinase.[2]

References

  1. ↑ Neufeld EF, Feingold DS, Hassid WZ (1959). "Enzymic phosphorylation of D-glucuronic acid by extracts from seedlings of Phaseolus aureus". Arch. Biochem. Biophys. 83 (1): 96–100. doi:10.1016/0003-9861(59)90014-1. PMID 13661996.
  2. ↑ Enzyme 2.7.1.43 at KEGG Pathway Database.


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