Glucuronate-1-phosphate uridylyltransferase
| Glucuronate-1-phosphate uridylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.44 | ||||||||
| CAS no. | 52228-05-4 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Glucuronate-1-phosphate uridylyltransferase (EC 2.7.7.44) is an enzyme that catalyzes the chemical reaction
The enzyme characterised from barley seedlings combines 1-phospho-α-D-glucuronic acid and uridine triphosphate to give uridine diphosphate glucuronic acid, with pyrophosphate (PPi) as a byproduct.[1][2]
This enzyme is a transferase, specifically one transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:1-phospho-alpha-D-glucuronate uridylyltransferase. Other names in common use include UDP-glucuronate pyrophosphorylase, UDP-D-glucuronic acid pyrophosphorylase, UDP-glucuronic acid pyrophosphorylase, and uridine diphosphoglucuronic pyrophosphorylase.[3]
References
- ↑ Roberts RM (August 1971). "The formation of uridine diphosphate-glucuronic acid in plants. Uridine diphosphate-glucuronic acid pyrophosphorylase from barley seedlings". The Journal of Biological Chemistry. 246 (16): 4995–5002. doi:10.1016/S0021-9258(18)61962-3. PMID 5570433.
- ↑ Schomburg, Dietmar; Stephan, Dörte (1997). "Glucuronate-1-phosphate uridylyltransferase". Enzyme Handbook. pp. 689–691. doi:10.1007/978-3-642-59025-2_125. ISBN 978-3-642-47773-7.
- ↑ Enzyme 2.7.7.44 at KEGG Pathway Database.
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