Galactose-1-phosphate thymidylyltransferase
| Galactose-1-phosphate thymidylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.32 | ||||||||
| CAS no. | 9023-25-0 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Galactose-1-phosphate thymidylyltransferase (EC 2.7.7.32) is an enzyme that catalyzes the chemical reaction
The enzyme characterised from Streptococcus faecalis combines thymidine triphosphate and α-D-galactose 1-phosphate to give dTDP-D-galactose, with pyrophosphate (PPi) as a byproduct.[1][2]
This enzyme is a transferase, specifically one transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase. Other names in common use include dTDP galactose pyrophosphorylase, galactose 1-phosphate thymidylyl transferase, thymidine diphosphogalactose pyrophosphorylase, thymidine triphosphate:alpha-D-galactose 1-phosphate, and thymidylyltransferase.[3]
References
- ↑ Pazur JH, Anderson JS (October 1963). "Thymidine triphosphate: alpha-D-galactose 1-phosphate thymidylyltransferase from Streptococcus faecalis grown on D-galactose". The Journal of Biological Chemistry. 238 (10): 3155–60. doi:10.1016/S0021-9258(18)48640-1. PMID 14085355.
- ↑ Schomburg, Dietmar; Stephan, Dörte (1997). "Galactose-1-phosphate thymidylyltransferase". Enzyme Handbook. pp. 635–637. doi:10.1007/978-3-642-59025-2_113. ISBN 978-3-642-47773-7.
- ↑ Enzyme 2.7.7.32 at KEGG Pathway Database.