Formate kinase

Formate kinase
Identifiers
EC no.2.7.2.6
CAS no.9026-65-7
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Formate kinase (EC 2.7.2.6) is an enzyme that catalyzes the chemical reaction

2D representation of the chemical structure of formic acid .
formic acid
 
Reversible left-right reaction arrow with minor forward substrate(s) from top left, minor forward product(s) to top right, minor reverse substrate(s) from bottom right and minor reverse product(s) to bottom left
ATP
ADP
 
2D representation of the chemical structure of Q27102049.
formyl phosphate

The enzyme characterised from the bacterium, Clostridium cylindrosporum, converts formic acid to formyl phosphate by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP).[1]

This enzyme is a transferases, specifically one transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:formate phosphotransferase.[2]

References

  1. ↑ Sly WS, Stadtman ER (1963). "Formate metabolism. II. Enzymatic synthesis of formyl phosphate and formyl coenzyme A in Clostridium cylindrosporum". J. Biol. Chem. 238 (8): 2639–2647. doi:10.1016/S0021-9258(18)67879-2. PMID 14063285.
  2. ↑ Enzyme 2.7.2.6 at KEGG Pathway Database.


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