Flavonol 7-O-beta-glucosyltransferase

Flavonol 7-O-beta-glucosyltransferase
Identifiers
EC no.2.4.1.237
CAS no.83682-90-0
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Flavonol 7-O-beta-glucosyltransferase (EC 2.4.1.237) is an enzyme that catalyzes the general chemical reaction

UDP-glucose + a flavonol UDP + a flavonol 7-O-β-D-glucoside

The enzyme characterised from Chrysanthemum segetum uses UDP-glucose to transfer a glucose unit to a specific phenolic hydroxy group of a flavonol, giving the corresponding flavonol 7-O-β-D-glucoside, with uridine diphosphate (UDP) as a byproduct. For example, quercetin is converted to quercimeritrin:[1]

 
 
Rightward reaction arrow with minor product(s) to top right
 
 
 
2D representation of the chemical structure of Q23069184.
quercimeritrin

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase. This enzyme is also called UDP-glucose:flavonol 7-O-glucosyltransferase.[2]

References

  1. ↑ Stich K, Halbwirth H, Wurst F, Forkmann G (1997). "UDP-glucose: flavonol 7-O-glucosyltransferase activity in flower extracts of Chrysanthemum segetum". Z. Naturforsch. C. 52 (3–4): 153–8. doi:10.1515/znc-1997-3-403. PMID 9167271.
  2. ↑ Enzyme 2.4.1.237 at KEGG Pathway Database.