Flavone 7-O-beta-glucosyltransferase

Flavone 7-O-beta-glucosyltransferase
Identifiers
EC no.2.4.1.81
CAS no.37332-50-6
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

Flavone 7-O-beta-glucosyltransferase (EC 2.4.1.81) is an enzyme that catalyzes the chemical reaction

 
 
Rightward reaction arrow with minor product(s) to top right
 
 
 

The two substrates of this enzyme characterised from parsley are the flavone, luteolin, and UDP-glucose. Its products are cynaroside and uridine diphosphate (UDP).[1]

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase. Other names in common use include UDP-glucose-apigenin beta-glucosyltransferase, UDP-glucose-luteolin beta-D-glucosyltransferase, uridine diphosphoglucose-luteolin glucosyltransferase, uridine diphosphoglucose-apigenin 7-O-glucosyltransferase, and UDP-glucosyltransferase. This enzyme participates in flavonoid biosynthesis.[2]

References

  1. ↑ Sutter A, Ortmann R, Grisebach H (1972). "Purification and properties of an enzyme from cell suspension cultures of parsley catalyzing the transfer of D-glucose from UDP-D-glucose to flavonoids". Biochim. Biophys. Acta. 258 (1): 71–87. doi:10.1016/0005-2744(72)90967-9. PMID 5058406.
  2. ↑ Enzyme 2.4.1.81 at KEGG Pathway Database.