DUSP13A

DUSP13A
Identifiers
AliasesDUSP13A, dual specificity phosphatase 13A, BEDP, MDSP, DUSP13
External IDsGeneCards: DUSP13A
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
3.1.3.16↗↗↗↗
3.1.3.48↗↗↗↗
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

128854680

n/a

Ensembl

ENSG00000293543

n/a

UniProt

Q6B8I1

n/a

RefSeq (mRNA)

NM_001007271

n/a

RefSeq (protein)

NP_001007272

n/a

Location (UCSC)n/an/a
PubMed search[1]n/a
Wikidata
View/Edit Human

Dual specificity protein phosphatase 13A is an enzyme that in humans is encoded by the DUSP13A gene.[2] This gene has previously been considered part of DUSP13, but that term includes the related gene, DUSP13B.[3] This protein has also been called "muscle-restricted dual-specificity phosphatase" (MDSP) to distinguish it from DUSP13B, which has been called "Testis- and skeletal-muscle-specific phosphatase" or "TMDP".[4][5]

Function

Members of the protein tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This gene encodes a dual specificity phosphatase that acts on both phosphotyrosine and phosphoserine/threonine residues. The encoded protein is expressed in skeletal muscle.[2]

References

Public Domain This article incorporates public domain material from websites or documents of the National Institutes of Health.
  1. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. 1 2 "DUSP13A dual specificity phosphatase 13A [ Homo sapiens (human) ]". Retrieved 2026-08-11.
  3. ↑ "DUSP13B dual specificity phosphatase 13B [ Homo sapiens (human) ]". Retrieved 2026-08-11.
  4. ↑ Park JE, Park BC, Kim HA, Song M, Park SG, Lee DH, Kim HJ, Choi HK, Kim JT, Cho S (August 2010). "Positive regulation of apoptosis signal-regulating kinase 1 by dual-specificity phosphatase 13A" (PDF). Cellular and molecular life sciences. 67 (15): 2619–2629. doi:10.1007/s00018-010-0353-3.
  5. ↑ "Q6B8I1 · DS13A_HUMAN". UniProt consortium. Retrieved 2026-08-11.
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