Cortisol O-acetyltransferase
| Cortisol O-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.27 | ||||||||
| CAS no. | 9076-48-6 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Cortisol O-acetyltransferase (EC 2.3.1.27) is an enzyme that was characterised from baboon brain and catalyzes a chemical reaction that converts the steroid hormone, cortisol, to a specific O-acetyl derivative.
The two substrates of this enzyme are cortisol and acetyl-CoA. Its products are hydrocortisone acetate and coenzyme A.[1]
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:cortisol O-acetyltransferase. Other names in common use include cortisol acetyltransferase, corticosteroid acetyltransferase, and corticosteroid-21-O-acetyltransferase.[2]
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