Caetano Reis e Sousa

Caetano Reis e Sousa
FRS FMedSci
Born
Caetano Maria Pacheco Pais dos Reis e Sousa

1968 (age 57–58)[1]
Lisbon, Portugal[1]
EducationAtlantic College
Alma materImperial College London (BSc)
University of Oxford (DPhil)
Scientific career
FieldsImmunology[2]
WorkplacesFrancis Crick Institute
Imperial College London
Imperial Cancer Research Fund
National Institute of Allergy and Infectious Diseases
ThesisPhagocytosis of antigens by Langerhans cells
Jonathan Austyn
Websitewww.crick.ac.uk/research/labs/caetano-reis-e-sousa

Caetano Maria Pacheco Pais dos Reis e Sousa (born 1968)[1] is a Portuguese scientist who is a principal group leader at the Francis Crick Institute.[2][3][4][5]

Education

Reis e Sousa was educated at Atlantic College in Wales,[5] Imperial College London (BSc) and the University of Oxford where he was awarded a Doctor of Philosophy degree in 1992 for research on dendritic cells, and the phagocytosis of antigens by Langerhans cells supervised by Jonathan Austyn.[6]

Career and research

After working as a postdoctoral researcher at the National Institute of Allergy and Infectious Diseases (NIAID) in the United States, with Ronald Germain, he joined the Imperial Cancer Research Fund (ICRF) in 1998.[7] He headed the Immunobiology Laboratory which became part of the Francis Crick Institute in 2015.[7] He is also a visiting professor of Immunology at Imperial College London[8][9] and King's College London and honorary professor at University College London (UCL).

Reis e Sousa's research centres on the mechanisms involved in sensing infection, cancer and tissue injury.[7] He has helped to define the cells and pathways involved in innate immune detection of RNA viruses, fungi and dead cells.[7][10][11][12]

Awards and honours

Reis e Sousa was elected a Fellow of the Royal Society (FRS) in 2019, and is also a Fellow of the Academy of Medical Sciences (FMedSci), a member of the European Molecular Biology Organization (EMBO)[13] and was made an Officer of the Order of Sant'Iago da Espada by the Government of Portugal in 2009.[7] He was awarded the Liliane Bettencourt Prize for Life Sciences[14] in 2008, Louis-Jeantet Prize for Medicine in 2017[1] and the Bial Award in Biomedicine in 2019[15].

References

  1. 1 2 3 4 "Caetano REIS E SOUSA". jeantet.ch. 4 October 2017.
  2. 1 2 Caetano Reis e Sousa publications indexed by Google Scholar
  3. ↑ "Caetano Reis e Sousa: Immunobiology Laboratory". crick.ac.uk.
  4. ↑ "Researchers: Caetano Reis e Sousa". crick.ac.uk.
  5. 1 2 Bashyam, Hema (2008). "Caetano Reis e Sousa: harnessing DC power". The Journal of Experimental Medicine. 205 (9): 1946–1947. doi:10.1084/jem.2059pi. ISSN 0022-1007. PMC 2526189. PMID 18762569.
  6. ↑ Reis e Sousa, Caetano Maria Pacheco Pais dos (1992). Phagocytosis of antigens by Langerhans cells (DPhil thesis). University of Oxford. OCLC 863542179. EThOS uk.bl.ethos.314901. Free access icon
  7. 1 2 3 4 5 Anon (2019). "Professor Caetano Reis e Sousa FMedSci FRS". royalsociety.org. London: Royal Society. Archived from the original on 24 April 2019. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
  8. ↑ Caetano Reis e Sousa publications from Europe PubMed Central
  9. ↑ "Professor Caetano Reis e Sousa". Imperial College London.
  10. ↑ Diebold, S. S. (2004). "Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA". Science. 303 (5663): 1529–1531. Bibcode:2004Sci...303.1529D. doi:10.1126/science.1093616. ISSN 0036-8075. PMID 14976261. S2CID 33144196. Closed access icon
  11. ↑ Kato, Hiroki; Takeuchi, Osamu; Sato, Shintaro; Yoneyama, Mitsutoshi; Yamamoto, Masahiro; Matsui, Kosuke; Uematsu, Satoshi; Jung, Andreas; Kawai, Taro; Ishii, Ken J.; Yamaguchi, Osamu; Otsu, Kinya; Tsujimura, Tohru; Koh, Chang-Sung; Reis e Sousa, Caetano; Matsuura, Yoshiharu; Fujita, Takashi; Akira, Shizuo (2006). "Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses". Nature. 441 (7089): 101–105. Bibcode:2006Natur.441..101K. doi:10.1038/nature04734. ISSN 0028-0836. PMID 16625202. S2CID 2270879. Closed access icon
  12. ↑ Pichlmair, A.; Schulz, O.; Tan, C. P.; Naslund, T. I.; Liljestrom, P.; Weber, F.; Reis e Sousa, C. (2006). "RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5'-Phosphates". Science. 314 (5801): 997–1001. Bibcode:2006Sci...314..997P. doi:10.1126/science.1132998. ISSN 0036-8075. PMID 17038589. S2CID 44366096. Closed access icon
  13. ↑ Cite error: The named reference membo was invoked but never defined (see the help page).
  14. ↑ "Caetano Reis e Sousa | Fondation Bettencourt Schueller". www.fondationbs.org.
  15. ↑ "2019 - Bial Award in Biomedicine". fundacaobial.com.
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