Centrobin is a protein that in humans is encoded by the CNTROB gene.[5]
It is a centriole-associated protein that asymmetrically localizes to the daughter centriole, and is required for centriole duplication and cytokinesis.[6]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000170037 – Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032782 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Tchernev VT, Mansfield TA, Giot L, Kumar AM, Nandabalan K, Li Y, et al. (January 2002). "The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins". Molecular Medicine. 8 (1). Cambridge, Mass.: 56–64. doi:10.1007/bf03402003. PMC 2039936. PMID 11984006.
- ↑ Zou C, Li J, Bai Y, Gunning W, Wazer D, Band V, et al. (November 2005). "Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication". The Journal of Cell Biology. 171 (3): 437–445. doi:10.1083/jcb.200506185. PMC 2171251. PMID 16275750.
Further reading
- Jeong Y, Lee J, Kim K, Yoo JC, Rhee K (June 2007). "Characterization of NIP2/centrobin, a novel substrate of Nek2, and its potential role in microtubule stabilization". Journal of Cell Science. 120 (Pt 12): 2106–2116. doi:10.1242/jcs.03458. PMID 17535851.
- Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, et al. (May 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–814. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
- Wan D, Gong Y, Qin W, Zhang P, Li J, Wei L, et al. (November 2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proceedings of the National Academy of Sciences of the United States of America. 101 (44): 15724–15729. Bibcode:2004PNAS..10115724W. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
