Biphenyl synthase
| Biphenyl synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.177 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Biphenyl synthase (EC 2.3.1.177) is an enzyme that catalyzes a biosynthesis of the polyketide, 3,5-dihydroxybiphenyl, from one unit of benzoyl-CoA and three of malonyl-CoA. It was characterised from the tree species Sorbus aucuparia and is part of the pathway that yields aucuparin, a phytoalexin.[1][2]
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:benzoyl-CoA malonyltransferase. This enzyme is also called BIS.[3]
References
- ↑ Liu B, Beuerle T, Klundt T, Beerhues L (2004). "Biphenyl synthase from yeast-extract-treated cell cultures of Sorbus aucuparia". Planta. 218 (3): 492–6. Bibcode:2004Plant.218..492L. doi:10.1007/s00425-003-1144-y. PMID 14595561.
- ↑ Liu, B.; Raeth, T.; Beuerle, T.; Beerhues, L. (2007). "Biphenyl synthase, a novel type III polyketide synthase". Planta. 225 (6): 1495–1503. doi:10.1007/s00425-006-0435-5. PMID 17109150.
- ↑ Enzyme 2.3.1.177 at KEGG Pathway Database.
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