Benzophenone synthase

Benzophenone synthase
Identifiers
EC no.2.3.1.151
CAS no.175780-21-9
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Benzophenone synthase (EC 2.3.1.151) is an enzyme that catalyzes a chemical reaction which takes one unit of 3-hydroxybenzoyl-CoA and combines this with three units of malonyl-CoA to give the benzophenone, 2,3',4,6-tetrahydroxybenzophenone, as product. Four units of coenzyme A and three of carbon dioxide are byproducts. The enzyme was characterised from the plant Centaurium erythraea. The product is an intermediate in the biosynthesis of xanthones.[1]

3-hydroxybenzoyl-CoA
+ 3
 
 
 
3 CO2
Rightward reaction arrow with minor product(s) to top right
 
 
 
2D representation of the chemical structure of Q27098205.
2,3',4,6-tetrahydroxybenzophenone
 

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase.[2]

References

  1. ↑ Beerhues L (April 1996). "Benzophenone synthase from cultured cells of Centaurium erythraea". FEBS Letters. 383 (3): 264–6. Bibcode:1996FEBSL.383..264B. doi:10.1016/0014-5793(96)00265-7. PMID 8925910.
  2. ↑ Enzyme 2.3.1.151 at KEGG Pathway Database.