Agmatine kinase
| Agmatine kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.3.10 | ||||||||
| CAS no. | 71061-39-7 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Agmatine kinase (EC 2.7.3.10) is an enzyme that catalyzes the reversible chemical reaction
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The enzyme characterised from the protozoans, Euglena oracilis and Ochramonas danica converts agmatine to the phosphagen, N(4)-phosphoagmatine, by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP).[1] The enzyme can phosphorylate L-arginine at a lower rate.[2]
This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with a nitrogenous group as acceptor. The systematic name of this enzyme class is ATP:agmatine N4-phosphotransferase. Other names in common use include phosphagen phosphokinase, and ATP:agmatine 4-N-phosphotransferase.[3]
References
- ↑ Piccinni E, Coppellotti O (1979). "Phosphagens in protozoa. II. Presence of phosphagen kinase in Ochramonas danica". Comp. Biochem. Physiol. 62B: 287–289.
- ↑ Petkowski, Janusz J.; Bains, William; Seager, Sara (2019). "Natural Products Containing 'Rare' Organophosphorus Functional Groups". Molecules. 24 (5): 866. doi:10.3390/molecules24050866. PMC 6429109. PMID 30823503.
- ↑ Enzyme 2.7.3.10 at KEGG Pathway Database.