Acetate kinase (diphosphate)
| Acetate kinase (diphosphate) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.2.12 | ||||||||
| CAS no. | 57657-58-6 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Acetate kinase (diphosphate) (EC 2.7.2.12) is an enzyme that catalyzes the chemical reaction
The enzyme characterised from the amoebozoa, Entamoeba histolytica, converts acetic acid to acetyl phosphate by transferring a phosphate group from pyrophosphoric acid, (PPi). Inorganic phosphate (Pi) is the byproduct.[1][2]
This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is diphosphate:acetate phosphotransferase. This enzyme is also called pyrophosphate-acetate phosphotransferase.[3]
References
- ↑ Reeves, Richard E.; Guthrie, John D. (1975). "Acetate kinase (Pyrophosphate). A fourth pyrophosphate-dependent kinase from Entamoeba histolytica". Biochemical and Biophysical Research Communications. 66 (4): 1389–1395. doi:10.1016/0006-291X(75)90513-6. PMID 172079.
- ↑ Fowler, Matthew L.; Ingram-Smith, Cheryl; Smith, Kerry S. (2012). "Novel Pyrophosphate-Forming Acetate Kinase from the Protist Entamoeba histolytica". Eukaryotic Cell. 11 (10): 1249–1256. doi:10.1128/EC.00169-12. PMC 3485911. PMID 22903977.
- ↑ Enzyme 2.7.2.12 at KEGG Pathway Database.
Categories: