2,4-dichlorophenol 6-monooxygenase
| 2,4-dichlorophenol 6-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.20 | ||||||||
| CAS no. | 92767-55-0 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
2,4-dichlorophenol 6-monooxygenase (EC 1.14.13.20) is an enzyme that catalyzes the chemical reaction
The four substrates of this enzyme are 2,4-dichlorophenol, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen, and a proton. Its products are 3,5-dichlorocatechol, oxidised NADP+, and water.[1][2]
The enzyme is a flavin-containing monooxygenase that uses molecular oxygen as oxidant and incorporates one of its atoms into the starting material. The systematic name of this enzyme class is 2,4-dichlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating). Other names in common use include 2,4-dichlorophenol hydroxylase, and 2,4-dichlorophenol monooxygenase. It can act on other chlorophenols.[1]
References
- 1 2 Enzyme 1.14.13.20 at KEGG Pathway Database.
- ↑ Beadle CA, Smith AR (1982). "The purification and properties of 2,4-dichlorophenol hydroxylase from a strain of Acinetobacter species". Eur. J. Biochem. 123 (2): 323–32. doi:10.1111/j.1432-1033.1982.tb19771.x. PMID 7075592.