Zinc finger protein 157

ZNF157
Identifiers
Aliases	ZNF157, HZF22, zinc finger protein 157
External IDs	OMIM: 300024; GeneCards: ZNF157
Gene location (Human) Chr. X chromosome (human) Band Xp11.3 Start 47,370,578 bp End 47,414,498 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence right uterine tube gonad olfactory zone of nasal mucosa islet of Langerhans cerebellar cortex cerebellar hemisphere right hemisphere of cerebellum anterior pituitary n/a More reference expression data BioGPS n/a
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 7712 n/a Ensembl ENSG00000147117 n/a UniProt P51786 n/a RefSeq (mRNA) NM_003446 n/a RefSeq (protein) NP_003437 n/a Location (UCSC) Chr X: 47.37 – 47.41 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Zinc finger protein 157 is a protein that in humans is encoded by the ZNF157 gene.

Function

This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. This gene is part of a gene cluster on chromosome Xp11.23.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.