Uracilylalanine synthase
| Uracilylalanine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.53 | ||||||||
| CAS no. | 113573-73-2 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Uracilylalanine synthase (EC 2.5.1.53) is an enzyme that catalyzes the chemical reaction
The two substrates of this plant enzyme are O-acetylserine and uracil. Its products are acetic acid and willardine.[1] The enzyme has been characterised from pea.[2] Although it transfers a 2-amino-2-carboxyethyl group from O-acetylserine, it has been shown not to be the same protein as cysteine synthase.[3]
This enzyme is a transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase. Other names in common use include O3-acetyl-L-serine acetate-lyase (adding uracil), isowillardiine synthase, willardiine synthase, and 3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase.[4]
References
- ↑ Kuo, YH; Lambein F (1978). "Biosynthesis of the uracilylalanines willardiine and isowillardiine in higher plants". Phytochemistry. 17 (9): 1571–1576. Bibcode:1978PChem..17.1571M. doi:10.1016/S0031-9422(00)94645-4.
- ↑ Ahmmad MAS; Maskall CS; Brown EG (1984). "Partial-purification and properties of willardiine and synthase activity from Pisum sativum". Phytochemistry. 23 (2): 265–270. doi:10.1016/S0031-9422(00)80315-5.
- ↑ Ikegami F, Kaneko M, Lambein F, Kuo, YH, Murakoshi I (1987). "Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum". Phytochemistry. 26 (10): 2699–2704. Bibcode:1987PChem..26.2699I. doi:10.1016/S0031-9422(00)83575-X.
- ↑ Enzyme 2.5.1.53 at KEGG Pathway Database.