TTYH3

TTYH3
Identifiers
Aliases	TTYH3, tweety family member 3
External IDs	OMIM: 608919; MGI: 1925589; GeneCards: TTYH3
Gene location (Human)
Chr.	Chromosome 7 (human)
End	2,664,802 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	140,634,786 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; stromal cell of endometrium; ; right hemisphere of cerebellum; ; monocyte; ; right frontal lobe; ; mucosa of ileum; ; prefrontal cortex; ; granulocyte; ; cingulate gyrus;
	Top expressed in
	ventricular zone; ; superior frontal gyrus; ; external carotid artery; ; internal carotid artery; ; primary visual cortex; ; piriform cortex; ; molar; ; genital tubercle; ; hand; ; mesenteric lymph nodes;
	More reference expression data
	n/a
Gene ontology
Molecular function	chloride channel activity; intracellular calcium activated chloride channel activity; volume-sensitive chloride channel activity;
Cellular component	integral component of membrane; plasma membrane; extracellular exosome; membrane; chloride channel complex;
Biological process	ion transmembrane transport; chloride transport; ion transport; chloride transmembrane transport; transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	80727
	78339
	ENSG00000136295
	ENSMUSG00000036565
	Q9C0H2
	Q6P5F7
	NM_025250
	NM_175274; NM_001308039; NM_001308040
	NP_079526
	NP_001294969; NP_780483
	Wikidata
View/Edit Human	View/Edit Mouse

Tweety family member 3 is a protein that in humans is encoded by the TTYH3 gene.^[5]

Function

This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel. [provided by RefSeq, Jul 2008].

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000136295 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000036565 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Tweety family member 3". Retrieved 2020-04-12.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000136295 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000036565 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Tweety family member 3". Retrieved 2020-04-12.

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