TAN-1057 C

TAN-1057 C and TAN-1057 D
	TAN-1057 C
	TAN-1057 D
Identifiers
CAS Number	128126-46-5 (TAN-1057 C) ; 128126-47-6 (TAN-1057 D) ;
3D model (JSmol)	Interactive image;
ChemSpider	7851330 ;
PubChem CID	9576889;
UNII	7TWX2V5P6Q ;
CompTox Dashboard (EPA)	DTXSID90155816 ;
	InChI InChI=1S/C13H25N9O3/c1-22-9(6-19-20-7-18-13(16)25)11(24)21-8(5-10(22)23)3-2-4-17-12(14)15/h7-9,19H,2-6H2,1H3,(H,21,24)(H4,14,15,17)(H3,16,18,20,25)/t8-,9+/m0/s1 Key: PNFFUPQADHHLMN-DTWKUNHWSA-N ; InChI=1/C13H25N9O3/c1-22-9(6-19-20-7-18-13(16)25)11(24)21-8(5-10(22)23)3-2-4-17-12(14)15/h7-9,19H,2-6H2,1H3,(H,21,24)(H4,14,15,17)(H3,16,18,20,25)/t8-,9+/m0/s1 Key: PNFFUPQADHHLMN-DTWKUNHWBI;
	SMILES O=C1N(C)[C@@H](C(=O)N[C@H](C1)CCC/N=C(\N)N)CNN\C=N\C(=O)N;
Properties
Chemical formula	C13H25N9O3
Molar mass	355.403 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

TAN-1057 C and TAN-1057 D are organic compounds found in the Flexibacter sp. PK-74 bacterium. TAN-1057 C and D are closely related structurally as diastereomers. Also related are TAN-1057 A and TAN-1057 B, isolated from the same bacteria. The four compounds have been shown to be an effective antibiotics against methicillin-resistant strains of Staphylococcus aureus which act through the inhibition of protein biosynthesis.^[1]

References

↑ Katayama, N; et al. (1993). "TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity". J. Antibiot. 46 (4): 606–613. doi:10.7164/antibiotics.46.606. PMID 8501003.

[Katayama-1] Katayama, N; et al. (1993). "TAN-1057 A-D, new antibiotics with potent antibacterial activity against methicillin-resistant Staphylococcus aureus. Taxonomy, fermentation and biological activity". J. Antibiot. 46 (4): 606–613. doi:10.7164/antibiotics.46.606. PMID 8501003.

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