Sulfoacetaldehyde dehydrogenase

Sulfoacetaldehyde dehydrogenase
Identifiers
EC no.1.2.1.73
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Sulfoacetaldehyde dehydrogenase (EC 1.2.1.73, SafD) is an enzyme with systematic name 2-sulfoacetaldehyde:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction:[2]

2D representation of the chemical structure of Q27102552.
sulfoacetaldehyde
+ NAD+
 
 
H2O
H+
Reversible left-right reaction arrow with minor forward substrate(s) from top left, minor forward product(s) to top right, minor reverse substrate(s) from bottom right and minor reverse product(s) to bottom left
H2O
H+
 
2D representation of the chemical structure of Q27104770.
sulfoacetic acid
+ NADH
 

This reaction is part of a bacterial pathway that can make use the amino group of taurine as a sole source of nitrogen for growth.

References

  1. ↑ Krejcík Z, Denger K, Weinitschke S, Hollemeyer K, Paces V, Cook AM, Smits TH (August 2008). "Sulfoacetate released during the assimilation of taurine-nitrogen by Neptuniibacter caesariensis: purification of sulfoacetaldehyde dehydrogenase". Archives of Microbiology. 190 (2): 159–68. Bibcode:2008ArMic.190..159K. doi:10.1007/s00203-008-0386-2. PMID 18506422.
  2. ↑ Enzyme 1.2.1.73 at KEGG Pathway Database.
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