Steroid-lactonase
| steroid-lactonase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.1.37 | ||||||||
| CAS no. | 37288-08-7 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Steroid-lactonase (EC 3.1.1.37) is an enzyme that catalyzes the reaction

testololactone
H2O

testolic acid
The enzyme characterised from Cephalosporium acremonium hydrolyses the steroid, testololactone, to testolic acid.[1][2]
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name testololactone lactonohydrolase.[3]
References
- ↑ Holmlund, Chester E.; Blank, Robert H. (1965). "Preparation and properties of a steroid lactonase". Archives of Biochemistry and Biophysics. 109: 29–35. doi:10.1016/0003-9861(65)90282-1. PMID 14281950.
- ↑ Schomburg, Dietmar; Salzmann, Margit (1991). "Steroid-lactonase". Enzyme Handbook 3. pp. 159–161. doi:10.1007/978-3-642-76463-9_33. ISBN 978-3-642-48962-4.
- ↑ Enzyme 3.1.1.37 at KEGG Pathway Database.
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