Major facilitator superfamily domain containing 14A

SLC71A1
Identifiers
Aliases	SLC71A1, HIAT1, major facilitator superfamily domain containing 14A
External IDs	MGI: 1201609; GeneCards: SLC71A1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	100,083,377 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	116,456,326 bp
RNA expression pattern
	Top expressed in
	smooth muscle tissue; ; islet of Langerhans; ; endometrium; ; corpus callosum; ; monocyte; ; tibial arteries; ; gonad; ; right lung; ; placenta; ; C1 segment;
	Top expressed in
	spermatocyte; ; spermatid; ; genital tubercle; ; parotid gland; ; seminal vesicula; ; Epithelium of choroid plexus; ; granulocyte; ; lacrimal gland; ; tail of embryo; ; retinal pigment epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	transporter activity;
Cellular component	membrane; integral component of membrane;
Biological process	transmembrane transport; acrosome assembly; spermatogenesis; spermatid development; spermatid nucleus differentiation; sperm mitochondrion organization;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	64645
	15247
	ENSG00000156875
	ENSMUSG00000089911
	Q96MC6
	P70187
	NM_033055
	NM_008246
	NP_149044
	NP_032272
	Wikidata
View/Edit Human	View/Edit Mouse

Major facilitator superfamily domain containing 14A (MFSD14A, HIAT1) is a protein that in humans is encoded by the gene SLC71A1 (formerly MFSD14A).^[5]^[6] MFSD14A is an atypical solute carrier of MFS type.^[7] HGNC:23363

MFSD14A cluster to AMTF1, together with MFSD9, MFSD10 and MFSD14B.^[8]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000156875 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000089911 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Major facilitator superfamily domain containing 14A".
↑ Lekholm E, Perland E, Eriksson MM, Hellsten SV, Lindberg FA, Rostami J, Fredriksson R (2017-01-01). "Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability". Frontiers in Molecular Neuroscience. 10: 11. doi:10.3389/fnmol.2017.00011. PMC 5263138. PMID 28179877.
↑ Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. PMID 27939446.
↑ Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9) 170142. doi:10.1098/rsob.170142. PMC 5627054. PMID 28878041.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000156875 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000089911 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Major facilitator superfamily domain containing 14A".

[6] Lekholm E, Perland E, Eriksson MM, Hellsten SV, Lindberg FA, Rostami J, Fredriksson R (2017-01-01). "Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability". Frontiers in Molecular Neuroscience. 10: 11. doi:10.3389/fnmol.2017.00011. PMC 5263138. PMID 28179877.

[7] Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. PMID 27939446.

[8] Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9) 170142. doi:10.1098/rsob.170142. PMC 5627054. PMID 28878041.

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