Richard Paulson

Richard J. Paulson
Born (1955-02-02) February 2, 1955
Prague, Czechoslovakia
CitizenshipAmerican
Alma materUniversity of California, Los Angeles (B.S., M.D.)
University of Southern California (M.S.)
Known forOocyte donation, reproductive aging, endometrial receptivity
Medical career
ProfessionMedical doctor, researcher, academic
InstitutionsKeck School of Medicine of USC

Richard J. Paulson (born February 2, 1955) is an American medical doctor, researcher, and academic specializing in reproductive endocrinology and infertility. He is Professor of Obstetrics and Gynecology and holder of the Alia Tutor Chair in Reproductive Medicine at the Keck School of Medicine of the University of Southern California (USC), where he has directed the USC Fertility program since 1986.[1] He is known for research on the use of oocyte donation to extend fertility in older women and for contributions to understanding endometrial receptivity, natural-cycle IVF, and oocyte cryopreservation.[2]

Paulson has authored or co-authored 300 peer-reviewed publications. According to Google Scholar, his publications have received more than 17,000 citations, and he has an h-index of 72.[3]

Early life and education

Paulson was born in Prague, Czechoslovakia, and became a United States citizen in 1972. He earned a Bachelor of Science in Physics, magna cum laude, from the University of California, Los Angeles (UCLA) in 1976, and his M.D. from the UCLA School of Medicine in 1980.[1][4]

Academic career

Paulson joined the USC faculty in 1986 as a Clinical Instructor and was promoted to associate professor in 1991 and full Professor in 1996.[1] He has served as Chief of the Division of Reproductive Endocrinology and Infertility and Director of the IVF Program at USC since 1995. In 2014, he was appointed to the endowed Alia Tutor Chair in Reproductive Medicine.[2] He also serves as Vice Chair for Administrative Affairs in the Department of Obstetrics and Gynecology.[5]

Research contributions

Paulson's research has focused on reproductive aging, embryo implantation,[6] oocyte donation, oocyte cryopreservation, and fertility preservation.[7][8]

Paulson's research helped establish oocyte donation as a treatment for age-related infertility. Studies conducted with colleagues demonstrated that pregnancy rates in women receiving donated oocytes were not significantly affected by recipient age, supporting the conclusion that reproductive aging is primarily related to egg quality rather than uterine function.[9][10] His group also reported some of the earliest successful pregnancies through oocyte donation in women over 50 and later examined maternal, neonatal, and psychosocial outcomes in this population.[11][12][13][14][15]

In a 1990 paper in Fertility and Sterility, Paulson characterized the concept of endometrial receptivity as a key determinant of embryo implantation success in human IVF.[16]

Beginning in 1989, Paulson and colleagues systematically evaluated IVF performed in unstimulated (natural) menstrual cycles.[17]

Paulson was a co-author on the first United States report of successful pregnancies following cryopreservation of human embryos, published in 1987.[18]

A 1988 paper co-authored by Paulson demonstrated that human ovarian theca cells produce renin, contributing to the understanding of the ovarian renin–angiotensin system and its possible role in ovarian hyperstimulation syndrome.[19]

Research by Paulson's group, published in 1994 demonstrated that vaginally administered progesterone achieves higher uterine tissue concentrations than the intramuscular route, findings that contributed to a clinical shift toward vaginal progesterone supplementation in IVF luteal phase support, an area that continues to be debated in the field.[20]

Paulson led early clinical research into oocyte cryopreservation at USC, helping establish one of the first fertility preservation programs using this technique in the United States in the early 2000s.[21]

Awards and recognition

  • The Best Doctors in America, listed continuously since 1994 (Woodward/White, Inc.)[1]
  • Excellence in Teaching Award, Keck School of Medicine of USC / Association of Professors of Gynecology and Obstetrics, 2004[2]
  • Howard and Georgeanna Jones Lifetime Achievement Award, American Fertility Association, 2005[2]
  • Distinguished Physician Award, Obstetrical and Gynecological Assembly of Southern California, 2012
  • ASRM Service Milestone Award, 2012
  • ASRM Star Award, 2012–2013
  • Honorary Membership, Middle East Fertility Society, 2021

Books

  • Lobo, RA; Mishell, DR Jr; Paulson, RJ; Shoupe, D (1997). Infertility, Contraception and Reproductive Endocrinology (4th ed.). Cambridge, Massachusetts: Blackwell Scientific Publications.
  • Paulson, RJ; Sachs, J (1998). Rewinding Your Biological Clock: Motherhood Late in Life. New York: W.H. Freeman and Company.
  • Goodwin, TM; Montoro, MN; Muderspach, LI; Paulson, RJ; Roy, S (2010). Management of Common Problems in Obstetrics and Gynecology (5th ed.). Oxford, UK: Wiley-Blackwell.

References

  1. 1 2 3 4 "Richard J. Paulson - Keck Medicine of USC". Retrieved 2026-06-04.
  2. 1 2 3 4 "Richard J. Paulson, MD, FACOG". HRC Fertility. Retrieved 2026-06-04.
  3. ↑ "USC Fertility - Now Part of HRC Fertility". USC Fertility. Retrieved 2026-06-04.
  4. ↑ "Richard J. Paulson". USC Today. Retrieved 2026-06-04.
  5. ↑ "Richard Paulson | USC Profiles". profiles.sc-ctsi.org. Retrieved 2026-06-04.
  6. ↑ "A surgeon thinks trans women can get pregnant". The Independent. 7 November 2017.
  7. ↑ Boodman, Sandra G. (26 January 2018). "Do women who donate their eggs run a health risk?". The Washington Post.
  8. ↑ Ferreira, Celeste (14 November 2018). "Audio story: Haven't completed your family by 35? Time to freeze your eggs". USC Today.
  9. ↑ Sauer, M. V.; Paulson, R. J.; Lobo, R. A. (1990-10-25). "A preliminary report on oocyte donation extending reproductive potential to women over 40". The New England Journal of Medicine. 323 (17): 1157–1160. doi:10.1056/NEJM199010253231702. ISSN 0028-4793. PMID 2136370.
  10. ↑ Sauer, M. V.; Paulson, R. J.; Lobo, R. A. (1992-09-09). "Reversing the natural decline in human fertility. An extended clinical trial of oocyte donation to women of advanced reproductive age". JAMA. 268 (10): 1275–1279. doi:10.1001/jama.268.10.1275. ISSN 0098-7484. PMID 1507373.
  11. ↑ Sauer, MV; Paulson, RJ; Lobo, RA (1993). "Pregnancy after age 50: application of oocyte donation to women after natural menopause". The Lancet. 341 (8841): 321–323. doi:10.1016/0140-6736(93)90136-2. PMID 8094110.
  12. ↑ Buster, John E. (1998), "Historical Evolution of Oocyte and Embryo Donation as a Treatment for Intractable Infertility", in Sauer, Mark V. (ed.), Principles of Oocyte and Embryo Donation, New York, NY: Springer, pp. 1–9, doi:10.1007/978-1-4612-1640-7_1, ISBN 978-1-4612-1640-7, retrieved 2026-06-04
  13. ↑ Paulson, R. J.; Thornton, M. H.; Francis, M. M.; Salvador, H. S. (1997). "Successful pregnancy in a 63-year-old woman". Fertility and Sterility. 67 (5): 949–951. doi:10.1016/s0015-0282(97)81413-6. ISSN 0015-0282. PMID 9130906.
  14. ↑ Paulson, Richard J.; Boostanfar, Robert; Saadat, Peyman; Mor, Eliran; Tourgeman, David E.; Slater, Cristin C.; Francis, Mary M.; Jain, John K. (2002-11-13). "Pregnancy in the sixth decade of life: obstetric outcomes in women of advanced reproductive age". JAMA. 288 (18): 2320–2323. doi:10.1001/jama.288.18.2320. ISSN 0098-7484. PMID 12425710.
  15. ↑ Steiner, Anne Z.; Paulson, Richard J. (2007). "Motherhood after age 50: an evaluation of parenting stress and physical functioning". Fertility and Sterility. 87 (6): 1327–1332. doi:10.1016/j.fertnstert.2006.11.074. ISSN 1556-5653. PMID 17292363.
  16. ↑ Paulson, R. J.; Sauer, M. V.; Lobo, R. A. (1990). "Embryo implantation after human in vitro fertilization: importance of endometrial receptivity". Fertility and Sterility. 53 (5): 870–874. doi:10.1016/s0015-0282(16)53524-9. ISSN 0015-0282. PMID 2110078.
  17. ↑ Paulson, R. J.; Sauer, M. V.; Lobo, R. A. (1989). "In vitro fertilization in unstimulated cycles: a new application". Fertility and Sterility. 51 (6): 1059–1060. doi:10.1016/s0015-0282(16)60746-x. ISSN 0015-0282. PMID 2498130.
  18. ↑ Marrs, R. P.; Brown, J.; Sato, F.; Ogawa, T.; Yee, B.; Paulson, R.; Serafini, P.; Vargyas, J. M. (1987). "Successful pregnancies from cryopreserved human embryos produced by in vitro fertilization". American Journal of Obstetrics and Gynecology. 156 (6): 1503–1508. doi:10.1016/0002-9378(87)90023-8. ISSN 0002-9378. PMID 3591863.
  19. ↑ "PNAS". PNAS. doi:10.1073/pnas.85.6.1957. PMC 279900. PMID 3279422. Retrieved 2026-06-04.
  20. ↑ Miles, R. A.; Paulson, R. J.; Lobo, R. A.; Press, M. F.; Dahmoush, L.; Sauer, M. V. (1994). "Pharmacokinetics and endometrial tissue levels of progesterone after administration by intramuscular and vaginal routes: a comparative study". Fertility and Sterility. 62 (3): 485–490. doi:10.1016/s0015-0282(16)56935-0. ISSN 0015-0282. PMID 8062942.
  21. ↑ "Egg banking in the United States: current status of commercially available cryopreserved oocytes". Fertility and Sterility. 99 (3). 2013-03-01. doi:10.1016/j.fertn. ISSN 0015-0282. Archived from the original on 2023-05-26.
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