RUS family member 1

RUSF1
Identifiers
Aliases	RUSF1, RUS, chromosome 16 open reading frame 58, C16orf58, RUS family member 1
External IDs	MGI: 2384572; GeneCards: RUSF1
Gene location (Human)
Chr.	Chromosome 16 (human)
End	31,509,309 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	127,897,342 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; left ovary; ; right ovary; ; right lobe of thyroid gland; ; right uterine tube; ; canal of the cervix; ; left lobe of thyroid gland; ; body of pancreas; ; body of uterus; ; right lobe of liver;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; yolk sac; ; zygote; ; right kidney; ; neural layer of retina; ; epithelium of small intestine; ; proximal tubule; ; genital tubercle; ; secondary oocyte;
	More reference expression data
	n/a
Orthologs
Databases	NCBI: entry; OMA: entry
	64755
	233913
	ENSG00000140688
	ENSMUSG00000030780
	Q96GQ5
	Q91W34
	NM_022744
	NM_145590; NM_001360882
	NP_073581
	NP_663565; NP_001347811
	Wikidata
View/Edit Human	View/Edit Mouse

RUS family member 1 is a protein which in humans is encoded by the RUSF1 gene (previously C16orf58).^[5] During root morphogenesis, the related plant protein is involved in ultraviolet B light-sensing.^[5] Not much has been reported about the function of the protein in mammals, but there is a domain of unknown function, DUF647, which may play a part in protein-protein interaction.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000140688 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030780 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 3 "RUSF1 - RUS family member 1". ncbi.nlm.nih.gov. Retrieved 2026-08-02.

External links

Human C16orf58 genome location and C16orf58 gene details page in the UCSC Genome Browser.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000140688 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030780 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] 1 2 3 "RUSF1 - RUS family member 1". ncbi.nlm.nih.gov. Retrieved 2026-08-02.

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