RNA exonuclease 5

REXO5
Identifiers
Aliases	REXO5, LOC81691, RNA exonuclease 5, NEF-sp
External IDs	MGI: 1919402; GeneCards: REXO5
Gene location (Human) Chr. Chromosome 16 (human) Band 16p12.3 Start 20,806,429 bp End 20,849,665 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 F2 Start 119,794,006 bp End 119,848,943 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis male germ cell sperm testicle gonad ventricular zone ganglionic eminence body of stomach right uterine tube Top expressed in spermatocyte seminiferous tubule spermatid Paneth cell genital tubercle medullary collecting duct fossa condyle otolith organ tail of embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nuclease activity exonuclease activity hydrolase activity RNA binding nucleic acid binding Cellular component nucleolus extracellular exosome nucleus Biological process nucleic acid phosphodiester bond hydrolysis Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 81691 434234 Ensembl ENSG00000005189 ENSMUSG00000030924 UniProt Q96IC2 n/a RefSeq (mRNA) NM_001144924 NM_001199053 NM_030941 NM_001004187 NM_028129 RefSeq (protein) NP_001138396 NP_001185982 NP_112203 n/a Location (UCSC) Chr 16: 20.81 – 20.85 Mb Chr 7: 119.79 – 119.85 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

RNA exonuclease 5 is a protein that in humans is encoded by the gene REXO5 (previously LOC81691). Not much has been reported about the function of this protein, but it is predicted to participate in ribosomal RNA (3’ end) processing.

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.