R6372

R6372
Identifiers
	IUPAC name 8-[1-(4-methylphenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;
CAS Number	2940-60-5;
PubChem CID	200932;
ChemSpider	173957;
Chemical and physical data
Formula	C22H27N3O
Molar mass	349.478 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1=CC=C(C=C1)C(C)N2CCC3(CC2)C(=O)NCN3C4=CC=CC=C4;
	InChI InChI=1S/C22H27N3O/c1-17-8-10-19(11-9-17)18(2)24-14-12-22(13-15-24)21(26)23-16-25(22)20-6-4-3-5-7-20/h3-11,18H,12-16H2,1-2H3,(H,23,26); Key:MBCUBRXUURKNCY-UHFFFAOYSA-N;

R6372 is a potent opioid analgesic drug from the spiropiperidine family, related to opioid designer drugs such as spirochlorphine. It has around 186x the potency of morphine, making it approximately twice the potency of fentanyl.^[1]

References

↑ Humblet C, Burnotte C, Evrard G, Durant F (1978-12-01). "8-[1-(4-Methylphenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 0.5 methanol:R6372". Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 34 (12): 3830–3832. Bibcode:1978AcCrB..34.3830H. doi:10.1107/S0567740878012388.

[1] Humblet C, Burnotte C, Evrard G, Durant F (1978-12-01). "8-[1-(4-Methylphenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 0.5 methanol:R6372". Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 34 (12): 3830–3832. Bibcode:1978AcCrB..34.3830H. doi:10.1107/S0567740878012388.

[1]

See also

References