Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1

QRSL1
Identifiers
Aliases	QRSL1, GatA, glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1, glutaminyl-tRNA amidotransferase subunit A, glutaminyl-tRNA amidotransferase subunit COXPD40
External IDs	OMIM: 617209; MGI: 1923813; GeneCards: QRSL1
Enzyme activity
Gene location (Human)
Chr.	Chromosome 6 (human)
End	106,668,417 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	43,777,741 bp
RNA expression pattern
	Top expressed in
	muscle of arm; ; biceps brachii; ; triceps brachii muscle; ; Skeletal muscle tissue of biceps brachii; ; thoracic diaphragm; ; vastus lateralis muscle; ; glutes; ; gastrocnemius muscle; ; gonad; ; right ventricle;
	Top expressed in
	substantia nigra; ; Paneth cell; ; retinal pigment epithelium; ; facial motor nucleus; ; digastric muscle; ; ciliary body; ; motor neuron; ; condyle; ; sternocleidomastoid muscle; ; fossa;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; ligase activity; ATP binding; glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity; amidase activity; protein binding; carbon-nitrogen ligase activity, with glutamine as amido-N-donor;
Cellular component	glutamyl-tRNA(Gln) amidotransferase complex; mitochondrion;
Biological process	regulation of protein stability; protein biosynthesis; mitochondrial translation; glutaminyl-tRNAGln biosynthesis via transamidation;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	55278
	76563
	ENSG00000130348
	ENSMUSG00000019863
	Q9H0R6
	Q9CZN8
	NM_018292
	NM_001081054
	NP_060762
	NP_001074523
	Wikidata
View/Edit Human	View/Edit Mouse

Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 is a protein that in humans is encoded by the QRSL1 gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000130348 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000019863 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1". Retrieved 2018-05-17.

Vieira AR, McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML (September 2008). "Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts". Genet. Med. 10 (9): 668–74. doi:10.1097/GIM.0b013e3181833793. PMC 2734954. PMID 18978678.
Nagao A, Suzuki T, Katoh T, Sakaguchi Y, Suzuki T (September 2009). "Biogenesis of glutaminyl-mt tRNAGln in human mitochondria". Proc. Natl. Acad. Sci. U.S.A. 106 (38): 16209–14. Bibcode:2009PNAS..10616209N. doi:10.1073/pnas.0907602106. PMC 2752530. PMID 19805282.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000130348 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000019863 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1". Retrieved 2018-05-17.

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References

Further reading