Phosphoethanolamine N-methyltransferase

Phosphoethanolamine N-methyltransferase
Identifiers
EC no.2.1.1.103
CAS no.171040-79-2
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Phosphoethanolamine N-methyltransferase (EC 2.1.1.103) is an enzyme that catalyzes the chemical reaction

2D representation of the chemical structure of phosphorylethanolamine .
phosphorylethanolamine
+ SAM
 
 
 
 
Rightward reaction arrow
 
 
 
2D representation of the chemical structure of Q27101920.
N-methylethanolamine phosphate
+ SAH
 

This is a methylation reaction in which the phosphorylethanolamine is converted to N-methylethanolamine phosphate. The methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH).[1]

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase. This enzyme is also called phosphoethanolamine methyltransferase. It is part of the biosynthetic pathway to phosphocholine.[2]

References

  1. ↑ Datko AH, Mudd SH (December 1988). "Enzymes of phosphatidylcholine synthesis in lemna, soybean, and carrot". Plant Physiology. 88 (4): 1338–48. doi:10.1104/pp.88.4.1338. PMC 1055762. PMID 16666464.
  2. ↑ Enzyme 2.1.1.103 at KEGG Pathway Database.


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