Naringenin 8-dimethylallyltransferase
| Naringenin 8-dimethylallyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.70 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Naringenin 8-dimethylallyltransferase (EC 2.5.1.70) is an enzyme characterised from Sophora flavescens that catalyzes a chemical reaction that converts naringenin to its 8-prenyl derivative by adding the 5-carbon unit from dimethylallyl pyrophosphate. This gives 8-prenylnaringenin (also called sophoraflavanone B), with pyrophosphate (PPi) as a byproduct:[1][2]
This enzyme is a transferase, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is dimethylallyl-diphosphate:naringenin 8-dimethylallyltransferase. It is also called N8DT and is part of the biosynthesis pathway to sophoraflavanone G.[3]
References
- ↑ Yamamoto H, Senda M, Inoue K (2000). "Flavanone 8-dimethylallyltransferase in Sophora flavescens cell suspension cultures". Phytochemistry. 54 (7): 649–55. Bibcode:2000PChem..54..649Y. doi:10.1016/S0031-9422(00)00198-9. PMID 10975499.
- ↑ Zhao P, Inoue K, Kouno I, Yamamoto H (2003). "Characterization of leachianone G 2"-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait cell suspension cultures". Plant Physiol. 133 (3): 1306–13. doi:10.1104/pp.103.025213. PMC 281625. PMID 14551337.
- ↑ Enzyme 2.5.1.70 at KEGG Pathway Database.