Naringenin 7-O-methyltransferase
| Naringenin 7-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.232 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Naringenin 7-O-methyltransferase (EC 2.1.1.232, NOMT) (full systematic name S-adenosyl-L-methionine:(2S)-5,7,4'-trihydroxyflavanone 7-O-methyltransferase) is a methyltransferase isolated from rice, which catalyzes the final step in the biosynthesis of sakuranetin from naringenin.[1][2] The chemical reaction is:
This is a methylation reaction in which the methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH). The enzyme was characterised from Oryza sativa. While the enzyme is not present in healthy rice leaves, it can be induced by treatment with ultraviolet radiation, jasmonic acid and copper chloride.[2]
References
- ↑ Enzyme 2.1.1.232 at KEGG Pathway Database.
- 1 2 Rakwal R, Agrawal GK, Yonekura M, Kodama O (June 2000). "Naringenin 7-O-methyltransferase involved in the biosynthesis of the flavanone phytoalexin sakuranetin from rice (Oryza sativa L.)". Plant Science. 155 (2): 213–221. Bibcode:2000PlnSc.155..213R. doi:10.1016/s0168-9452(00)00223-5. PMID 10814825.
External links
- Naringenin+7-O-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Category: