Naohisa Yahagi

Naohisa Yahagi
Alma materNiigata University (MD)
University of Tokyo (PhD)
OccupationsProfessor of Medicine
Physician
Researcher
EmployerKeio University School of Medicine
Known forendoscopic submucosal dissection (ESD)

Naohisa Yahagi is a Japanese physician and endoscopist who serves as Professor of Medicine and Director of the Division of Research and Development for Minimally Invasive Treatment at the Cancer Center, Keio University School of Medicine in Tokyo.[1][2] He is known for contributions to the development of a technique termed endoscopic submucosal dissection, used for resection of polyps and early stage cancers of the gastrointestinal tract.[3][4]

Education and career

Yahagi received an M.D. from Niigata University School of Medicine in 1987.[5][6] He completed residency in internal medicine at Tokyo Teishin Hospital in 1989, then served as a staff gastroenterologist there from 1989 to 1990.[7][8] In 1990 he joined the First Department of Internal Medicine at the University of Tokyo and later became an assistant professor in 1997.[9] He earned a Ph.D. from the University of Tokyo in 1998.[10] From 2005 to 2010 he served as Director of the Department of Gastroenterology and the Digestive Endoscopy Unit at Toranomon Hospital in Tokyo.[11][12] In 2010 he moved to Keio University School of Medicine, where he is Professor of Medicine and Director of the Division of Research and Development for Minimally Invasive Treatment at the Cancer Center.[13][14] He served as President of the 108th Congress of the Japan Gastroenterological Endoscopy Society at Japan Digestive Disease Week 2024 in Kobe.[15][16]

Research and contributions

In 2004 Yahagi and colleagues reported an early technique of endoscopic submucosal dissection (ESD) for early gastric cancer using the tip of an electrosurgical snare, which influenced later ESD practice.[17] He later authored an editorial on the development of colorectal ESD, reflecting ongoing contributions to indications, technique and dissemination.[18] Yahagi is a co-author of the Japan Gastroenterological Endoscopy Society guidelines for colorectal ESD and EMR, including editions published in 2015 and 2020.[19][20]

Yahagi and collaborators developed the DualKnife as an improved version of the Flex knife for ESD, and described its use in clinical practice.[21][22] Subsequent device iterations such as DualKnife J have been reported by the manufacturer for combined injection and dissection during ESD procedures.[23] According to Stanford’s Center for Asian Health, Yahagi has been described as an inventor of several ESD devices, including the Flex knife and DualKnife series, as well as a developer of the water pressure method and string clip suturing method.[24]

Yahagi and colleagues introduced the water pressure method for ESD in 2017, reporting improved visualization and countertraction under water immersion, with subsequent publications evaluating its application in anatomically challenging locations such as the cervical esophagus.[25][26] He and co-authors also described the string clip suturing method in 2016, followed by pilot studies assessing its feasibility for defect closure after ESD.[27][28]

Achievements and honors

Yahagi served as President of the 108th Congress of the Japan Gastroenterological Endoscopy Society during Japan Digestive Disease Week 2024 in Kobe.[29] He has been invited to lecture and perform live demonstrations at numerous international meetings in endoscopy.[30]

References

  1. ↑ "Naohisa Yahagi, MD, PhD". American Society for Gastrointestinal Endoscopy. Retrieved 16 September 2025.
  2. ↑ "Details of a Researcher – Yahagi, Naohisa". Keio University Researchers Information System. Keio University. 8 July 2025. Retrieved 16 September 2025.
  3. ↑ Yahagi, Naohisa; Nishizawa, Toshihiro; Akimoto, Teppei; Ochiai, Yasutoshi; Goto, Osamu (December 2016). "New endoscopic suturing method: string clip suturing method". Gastrointestinal Endoscopy. 84 (6): 1064–1065. doi:10.1016/j.gie.2016.05.054. PMID 27327846.
  4. ↑ Yahagi, Naohisa; Nishizawa, Toshihiro; Sasaki, Motoki; Ochiai, Yasutoshi; Uraoka, Toshio (31 July 2017). "Water pressure method for duodenal endoscopic submucosal dissection". Endoscopy. 49 (10): E227–E228. doi:10.1055/s-0043-113556. PMID 28759932.
  5. ↑ "Prof Naohisa Yahagi". Asian Pacific Digestive Week 2025. APDW 2025 Singapore. Retrieved 16 September 2025.
  6. ↑ "Naohisa Yahagi – Speaker Profile". eMedEvents. Retrieved 16 September 2025.
  7. ↑ "Naohisa Yahagi – Speaker Profile". eMedEvents. Retrieved 16 September 2025.
  8. ↑ "CURRICULUM VITAE – Naohisa Yahagi". Yumpu. 8 January 2011. Retrieved 16 September 2025.
  9. ↑ "CURRICULUM VITAE – Naohisa Yahagi". Yumpu. 8 January 2011. Retrieved 16 September 2025.
  10. ↑ "Prof Naohisa Yahagi". Asian Pacific Digestive Week 2025. APDW 2025 Singapore. Retrieved 16 September 2025.
  11. ↑ "Prof Naohisa Yahagi". Asian Pacific Digestive Week 2025. APDW 2025 Singapore. Retrieved 16 September 2025.
  12. ↑ "CURRICULUM VITAE – Naohisa Yahagi". Yumpu. 8 January 2011. Retrieved 16 September 2025.
  13. ↑ "Naohisa Yahagi, MD, PhD". American Society for Gastrointestinal Endoscopy. Retrieved 16 September 2025.
  14. ↑ "CURRICULUM VITAE – Naohisa Yahagi". Yumpu. 8 January 2011. Retrieved 16 September 2025.
  15. ↑ "The 108th Congress of the Japan Gastroenterological Endoscopy Society, President: Naohisa Yahagi". JDDW 2024 Kobe. Japan Digestive Disease Week. 2024. Retrieved 16 September 2025.
  16. ↑ "Message from JDDW 2024 Meetings' & Congress' Presidents". JDDW 2024 Kobe. Japan Digestive Disease Week. 2024. Retrieved 16 September 2025.
  17. ↑ Yahagi, Naohisa; Fujishiro, Mitsuru; Kakushima, Naomi; Kodashima, Shin-ei; Muraki, Yasuhiro; Omata, Masao (2004). "Endoscopic submucosal dissection for early gastric cancer using the tip of an electrosurgical snare (thin type)". Digestive Endoscopy. 16: 34–38. doi:10.1111/j.1443-1661.2004.00313.x.
  18. ↑ Yahagi, Naohisa (May 2022). "Development of colorectal endoscopic submucosal dissection". Digestive Endoscopy. 34 (Suppl 2): 95–98. doi:10.1111/den.14229. PMID 35132686.
  19. ↑ Tanaka, Shinji; Kashida, Hiroshi; Saito, Yutaka; Yahagi, Naohisa; Yamano, Hiroyuki; Saito, Shigeki (May 2015). "JGES guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection". Digestive Endoscopy. 27 (4): 417–434. doi:10.1111/den.12456. PMID 25652022.
  20. ↑ Tanaka, Shinji; Kashida, Hiroshi; Saito, Yutaka; Yahagi, Naohisa; Yamano, Hiroyuki; Saito, Shigeki (2020). "Japan Gastroenterological Endoscopy Society guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection". Digestive Endoscopy. 32 (2): 219–239. doi:10.1111/den.13545. PMID 31566804.
  21. ↑ Yahagi, Naohisa; Uraoka, Toshio; Ida, Yosuke; Hosoe, Naoki; Nakamura, Rieko; Kitagawa, Yuko; Ogata, Haruhiko; Hibi, Toshifumi (2011). "Endoscopic submucosal dissection using the Flex and Dual knives". Techniques in Gastrointestinal Endoscopy. 13. Elsevier: 74–78. doi:10.1016/j.tgie.2011.02.006. Retrieved 16 September 2025.
  22. ↑ Yahagi, Naohisa (May 2022). "Development of colorectal endoscopic submucosal dissection". Digestive Endoscopy. 34 (Suppl 2): 95–98. doi:10.1111/den.14229. PMID 35132686.
  23. ↑ "Olympus Launches the DualKnife J, an ESD Electrosurgical Knife that Shortens Procedure Time". PR Newswire. Olympus Corporation of the Americas. 30 May 2018. Retrieved 16 September 2025.
  24. ↑ "Naohisa Yahagi, MD". Stanford Center for Asian Health Research and Education. Stanford University. Retrieved 16 September 2025.
  25. ↑ Yahagi, Naohisa; Nishizawa, Toshihiro; Sasaki, Motoki; Ochiai, Yasutoshi; Uraoka, Toshio (31 July 2017). "Water pressure method for duodenal endoscopic submucosal dissection". Endoscopy. 49 (10): E227–E228. doi:10.1055/s-0043-113556. PMID 28759932.
  26. ↑ Masunaga, Teppei; Kato, Motohiko; Yahagi, Naohisa (2021). "Successful endoscopic submucosal dissection using the water pressure method for cervical esophageal cancer". Digestive Endoscopy. 33 (3): 479–480. doi:10.1111/den.13973. PMID 33788959.
  27. ↑ Yahagi, Naohisa; Nishizawa, Toshihiro; Akimoto, Teppei; Ochiai, Yasutoshi; Goto, Osamu (December 2016). "New endoscopic suturing method: string clip suturing method". Gastrointestinal Endoscopy. 84 (6): 1064–1065. doi:10.1016/j.gie.2016.05.054. PMID 27327846.
  28. ↑ Nishizawa, Toshihiro; Akimoto, Teppei; Uraoka, Toshio; Mitsunaga, Yasushi; Maehata, Takaaki; Ochiai, Yasutoshi; Goto, Osamu; Kanai, Takanori; Yahagi, Naohisa (April 2018). "Endoscopic string clip suturing method: a prospective pilot study". Gastrointestinal Endoscopy. 87 (4): 1074–1078. doi:10.1016/j.gie.2017.11.007. PMID 29154910.
  29. ↑ "The 108th Congress of the Japan Gastroenterological Endoscopy Society, President: Naohisa Yahagi". JDDW 2024 Kobe. Japan Digestive Disease Week. 2024. Retrieved 16 September 2025.
  30. ↑ "Prof Naohisa Yahagi". Asian Pacific Digestive Week 2025. APDW 2025 Singapore. Retrieved 16 September 2025.
This page is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.